Product Name:25-Hydroxycholesterol

Alias: 25-HYDROXYCHOLESTEROL;3BETA,25-DIHYDROXY-5-CHOLESTENE;5-CHOLESTEN-3-BETA,25-DIOL;5-CHOLESTENE-3BETA,25-DIOL;25-Hydroxycholesterol(notdeuterated);Cholest-5-ene-3,25-diol,(3.beta.)-;Chemicalbook5-cholestene-3β,25-diol;(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

CAS No.: 2140-46-7

Molecular formula: C₂₇H₄₆O₂

Molecular weight: 402.6529

25-Hydroxycholesterol is a metabolite of cholesterol produced and secreted by macrophages in response to toll-like receptor (TLR) activation. 25-Hydroxycholesterol effectively and selectively inhibits IgA production by B cells with EC50 of about 65 nM.